Medicare Part B Prior Authorization and Step Therapy


In this section

Select Part B drugs require Prior Authorization before they can be administered. The approval or denial is based on the plan design and focuses on safety and proper medication use. 

In addition, some Part B drugs will require Step Therapy, a form of utilization management that requires you to first try a preferred drug to treat a medical condition before we will cover another, non-preferred drug for that condition. Drugs that require step therapy are marked with an "ST" in the Medicare Part B Prior Authorization List below. 

Part B Prior Authorization List (effective 01/01/2026)

Part B Step Therapy (effective 01/01/2026)

Part B Prior Authorization Criteria 

When evaluating coverage requests for Part B drugs, MercyOne Health Plan follows National Coverage Determinations for all drugs on our Part B Prior Authorization List except for those listed below, which include plan-specific criteria. 

Select a drug name below to review prior authorization criteria. Drugs are listed in alphabetical order. 


 

Abraxane Med B Jurisdiction 6 (IL MN WI) and K (CT MA ME NH NY RI VT) 3861-A P2025

Aranesp Med B Jurisdiction J (AL, GA, TN) and M (NC, SC, VA, WV) 5564-A P2024

Beovu Med B Jurisdiction 6 (IL MN WI) and K (CT MA ME NH NY RI VT) 3828-A P2025

Bevacizumab and biosimilars Med B Jurisdiction 6 and K (CT IL MA ME MN NH NY RI VT WI) 3834-A P2025

Bisphosphonate Drug Therapy Med B Jurisdiction 5 and 8 (IA, KS, MO, NE, IN, MI) 4367-A P2024

Botox Med B Jurisdiction 15 (KY OH) 5204-A P2024

Botox Med B Jurisdiction J (AL GA TN) and M (NC SC VA WV) 5218-A P2024

Botox Med B Jurisdiction N (FL PR USVI) 2163-A P2024

Botulinum Toxins Med B Jurisdiction 5 and 8 (IA KS MO NE IN MI) 4825-A P2024

Botulinum Toxins Med B Jurisdiction 6 (IL MN WI) and K (CT MA ME NH NY RI VT) 3812-A P2024

Botulinum Toxins Med B Jurisdiction E (AS, CA, GU, HI, MP, NV) 5524-A P2024

Botulinum Toxins Med B Jurisdiction H (AR CO LA MS NM OK TX) and L (DC DE MD NJ PA) 4499-A P2024a

Camcevi Med B Jurisdiction 6 (IL MN WI) and K (CT MA ME NH RI VT) 5133-A P2025

Camcevi Med B Jurisdiction J (AL, GA, TN) and Jurisdiction M (NC, SC, VA, WV) 5743-A P2025

CroFab Med B Jurisdiction 05 and 08 (IA, IN, KS, MI, MO, NE) 4814-A P2024

Cytogam Med B Jurisdiction 05 and 08 (IA, IN, KS, MI, MO, NE) 4805-A P2024

Daxxify Med B Jurisdiction 6 (IL, MN, WI) and K (CT, MA, ME, NH, NY, RI, VT) 6578-A P2024a

Daxxify Med B Jurisdiction N (FL PR USVI) 6354-A P2024a

Dextenza Med B Jurisdiction J (AL, GA, TN) and M (NC, SC, VA, WV) 5205-A P2024_R

Dextenza Med B Jurisdiction J (AL, GA, TN) and M (NC, SC, VA, WV) 5205-A P2025

Dysport Med B Jurisdiction 15 (KY OH) 5236-A P2024

Dysport Med B Jurisdiction J (AL, GA, TN) and M (NC, SC, VA, WV) 5239-A P2024

Dysport Med B Jurisdiction N (FL, PR, USVI) 2164-A P2024

Eligard Med B Jurisdiction 06 (IL MN WI) and K (CT MA ME NH NY RI VT) 3959-A P2025

Epogen-Procrit-Retacrit Med B Jurisdiction J (AL, GA, TN) and M (NC, SC, VA, WV) 5563-A P2024

Epogen-Procrit-Retacrit-Aranesp Med B Jurisdiction 05 (IA, KS, MO, NE) and 08 (IN, MI) 4844-A P2024

Epogen-Procrit-Retacrit-Aranesp Med B Jurisdiction 15 (KY, OH) 5271-A P2024

Eylea and Biosimilars Med B Jurisdiction J (AL GA TN) and M (NC SC VA WV) 5206-A P2025a

Eylea-Eylea HD and Biosimilars Med B Jurisdiction 06 (IL MN WI) and K (CT MA ME NH NY RI VT) 3830-A P2025a

Filgrastim products Med B Jurisdiction J (AL, GA, TN) and M (NC, SC, VA, WV) 4490-A P2025

Granix Med B Jurisdiction J (AL, GA, TN) and M (SC, NC, VA, WV) 4489-A P2024

Hepagam B Med B Jurisdiction 05 and 08 (IA, IN, KS, MI, MO, NE) 4806-A P2024

Hyaluronans Med B Jurisdiction 6 (IL MN WI) and K (CT MA ME NH NY RI VT) 3832-A P2025

Hyaluronic Acid Injections Med B Jurisdiction J (AL GA TN) and M (NC SC WV VA) 5674-A P2025

Ibandronate Med B Jurisdiction 6 (IL, MN, WI) and K (CT, MA, ME, NH, NY, RI, VT) 3882-A P2024

Iluvien Med B Jurisdiction J (AL, GA, TN) and M (NC, SC, VA, WV) 5207-A P2025a

IMIG Med B Jurisdiction 05 and 08 (IA, IN, KS, MI, MO, NE) 4807-A P2024

infliximab Med B Jurisdiction J (AL,GA,TN) and Jurisdiction M (SC,VA,WV,NC) 4535-A P2024

infliximab products Med B Jurisdiction 6 (IL MN WI) and K (CT MA ME MN NH NY RI VT) 3938-A P2024

Intraarticular Knee Injections of Hyaluronan Med B Jurisdiction 5 (IA KS MO NE) and 8 (IN MI) 4877-A P2025

IUD Med B Jurisdiction 6 (IL, MN, WI) and K (CT, MA, ME, NH, NY, RI, VT) 5181-A P2025

IUD Med B Jurisdiction H (AR CO LA MS NM OK TX) and L (DC DE MD NJ PA) 6310-A P2025

IUD Med B Jurisdiction N (FL PR USVI) 6311-A P2025

IVIG Med B Jurisdiction 15 (KY, OH) 5317-A P2024a

IVIG Med B Jurisdiction 05 and 08 (IA, KS, MO, NE, IN, MI) 4792-A P2024a

IVIG Med B Jurisdiction 6 and K (CT IL MA ME MN NH NY RI VT WI) 3950-A P2025a

IVIG Med B Jurisdiction E (AS CA GU HI MP NV) 5526-A P2024a

IVIG Med B Jurisdiction F (AK AZ ID ND MT OR SD UT WA WY) 2111-A P2024a

IVIG Med B Jurisdiction J (AL GA TN) and M (NC SC VA WV) 4451-A P2024a

IVIG Med B Jurisdiction L and H (DC, DE, MD, NJ, PA, AR, CO, LA, MS, NM, OK, TX) 3997-A P2024a

IVIG Med B Jurisdiction N (FL PR USVI) 2112-A P2024a

Lemtrada Med B Jurisdiction J (AL GA TN) and M (NC SC VA WV) 5316-A P2025

Leukine Med B Jurisdiction J (AL, GA, TN) and M (SC, NC, VA, WV) 4488-A P2024

leuprolide depot-Lupron Depot Med B Jurisdiction 6 (IL MN WI) and K (CT MA ME NH NY RI VT) 3958-A P2025

leuprolide depot-Lupron Depot-Lutrate Med B Jurisdiction J (AL GA TN) and M (NC SC VA WV) 5748-A P2025

Lucentis and Biosimilars Med B Jurisdiction 6 (IL MN WI) and K (CT MA ME NH NY RI VT) 3831-A P2025

Luxturna Med B Jurisdiction J (AL, GA, TN) and Jurisdiction M (SC, VA, WV, NC) 4545-A P2025

Mircera Med B Jurisdiction 05 (KS, IA, MO, NE) and 08 (IN, MI) 5194-A P2024

Mircera Med B Jurisdiction J (AL, GA, TN) and M (NC, SC, VA, WV) 5565-A P2024

Myobloc Med B Jurisdiction 15 (KY OH) 5237-A P2024

Myobloc Med B Jurisdiction J (AL, GA, TN) and M (NC, SC, VA, WV) 5240-A P2024

Myobloc Med B Jurisdiction N (FL PR USVI) 2165-A P2024

Nplate Med B Jurisdiction 15 (KY OH) 5333-A P2024

octreotide acetate for injectable suspension-Sandostatin LAR Med B Jurisdiction J (AL GA TN) and M (NC SC VA WV) 5260-A P2025

Paclitaxel Med B Jurisdiction 6 (IL MN WI) and K (CT MA ME NH NY RI VT) 3862-A P2025

Pegfilgrastim products Med B Jurisdiction J (AL GA TN) and M (NC SC VA WV) 4491-A P2024

Prolia and Biosimilars Med B Jurisdiction 6 (IL MN WI) and K (CT MA ME NH NY RI VT) 3835-A P2024c

Rituxan Hycela Med B Jursidiction J (AL, GA, TN) and M (NC, SC, VA, WV) 4487-A P2025

Rituximab and Biosimilars Med B Jurisdiction 15 (KY OH) 5332-A P2025

Rituximab Med B Jurisdiction 05 (IA KS MO NE) and 8 (IN MI) 4892-A P2025

Rituximab Med B Jurisdiction 6 (IL MN WI) and K (CT MA ME NH NY RI VT) 3868-A P2025a

Rituximab products Med B Jurisdiction J (AL GA TN) Jurisdiction M (NC SC VA WV) 4452-A P2025

Rolvedon Med B Jurisdiction J (AL, GA, TN) and M (NC, SC, VA, WV) 5998-A P2024

SCIG Med B Jurisdiction 05 and 08 (IA KS MO NE IN MI) 4803-A P2024

SCIG Med B Jurisdiction N (FL PR USVI) 5765-A P2024

SCIG Med B Jurisdictions L and H (DC, DE, MD, NJ, PA, AR, CO, LA, MS, NM, OK, TX) 5766-A P2024

Soliris and Biosimilars Med B Jurisdiction 6 (IL MN WI) and K (CT MA ME NH NY RI VT) 3826-A P2024b_R

Testosterone Supplementation Med B Jurisdiction E (AS CA GU HI MP NV) 5514-A P2025

Testosterone Supplementation Med B Jurisdiction E (AS CA GU HI MP NV) and F (AK AZ ID MT ND OR SD UT WA WY) 5514-A P2025a

Testosterone Supplementation Med B Jurisdiction F (AK, AZ, ID, MT, ND, OR, SD, UT, WA, WY) 2225-A P2025

Testosterone Supplementation Med B Jurisdiction J (AL GA TN) and M (NC SC VA WV) 5777-A P2025

Trelstar Med B Jurisdiction 06 (IL MN WI) and K (CT MA ME NH NY RI VT) 3941-A P2025

Trelstar Med B Jurisdiction J (AL GA TN) and M (NC SC VA WV) 5745-A P2025

Triptodur Med B Jurisdiction 6 (IL MN WI) and K (CT MA ME NH NY RI VT) 3942-A P2025

Vabysmo Med B Jurisdiction 6 and K (CT IL MA ME MN NH NY RI VT WI) 5436-A P2025

Xeomin Med B Jurisdiction 15 (KY OH) 5238-A P2024

Xeomin Med B Jurisdiction J (AL, GA, TN) and M (NC, SC, VA, WV) 5241-A P2024

Xeomin Med B Jurisdiction N (FL PR USVI) 2166-A P2024

Xgeva and Biosimilars Med B Jurisdiction 6 (IL MN WI) and K (CT MA ME NH NY RI VT) 3836-A P2024c

Xofigo Med B Jurisdiction J (AL, GA, TN) and M (NC, SC, VA, WV) 5261-A P2024

Xolair-Omlyclo Med B Jurisdiction 06 (IL, MN, WI) and K (CT, MA, ME, MN, NH, NY, RI, VT) 3824-A P2025

Zoladex Med B Jurisdiction 6 (IL MN WI) and K (CT MA ME NH NY RI VT) 3943-A P2025

Zoladex Med B Jurisdiction J (AL GA TN) and M (NC SC VA WV) 5744-A P2025

This page was last updated 01/01/2026